What is Male Infertility?

Male infertility is a condition that affects a man’s ability to contribute to conception. It is defined as the inability to conceive a child after one year of regular, unprotected intercourse. Male infertility can be caused by a variety of factors that impact sperm production, function, or delivery. It accounts for approximately 40-50% of infertility cases in couples and can be the sole reason or a contributing factor to difficulties in achieving pregnancy.

Semen analysis test

Causes of Male Infertility

Conditions that impact the production or quality of sperm include:

+ Low Sperm Count (Oligospermia): Fewer than 15 million sperm per milliliter of semen.

+ No Sperm Production (Azoospermia): Absence of sperm in the ejaculate.

+ Poor Sperm Motility (Asthenozoospermia): Slow or weak sperm movement, which reduces the chances of reaching and fertilizing an egg.

+ Abnormal Sperm Morphology (Teratozoospermia): Abnormally shaped sperm, affecting their ability to penetrate the egg.
Hormones such as testosterone and follicle-stimulating hormone (FSH) are crucial for sperm production. Conditions like hypogonadism, where hormone levels are low, can lead to poor sperm production and quality.
Blockages or damage in the reproductive tract can prevent sperm from being released, as seen in conditions like:

+ Varicocele: Enlarged veins in the scrotum that can impair sperm production.

+ Obstructions: Blockages in the vas deferens or epididymis that prevent sperm from being ejaculated.
Chromosomal abnormalities or genetic conditions, such as Klinefelter syndrome or Y-chromosome microdeletions, can impact sperm production or function.
Exposure to toxins, smoking, excessive alcohol consumption, recreational drug use, and poor diet can negatively affect sperm health. High heat exposure, obesity, and certain medications can also contribute to infertility.
Infections like sexually transmitted infections (STIs), mumps orchitis, or conditions like diabetes and autoimmune diseases can damage the reproductive organs and impair fertility.
The most common test to evaluate sperm count, motility, morphology, and overall semen quality.
Blood tests to assess levels of testosterone, FSH, and other hormones that regulate sperm production.
Used to identify chromosomal or genetic abnormalities affecting fertility.
A procedure to evaluate sperm production directly from the testes, especially in cases of azoospermia.

Diagnosis of Male Infertility

Diagnosing male infertility typically involves a combination of medical history, physical examination, and specialized testing, including:

Diagnosis of Male Infertility

Diagnosing male infertility typically involves a combination of medical history, physical examination, and specialized testing, including:

The most common test to evaluate sperm count, motility, morphology, and overall semen quality.
Blood tests to assess levels of testosterone, FSH, and other hormones that regulate sperm production.
Used to identify chromosomal or genetic abnormalities affecting fertility.
A procedure to evaluate sperm production directly from the testes, especially in cases of azoospermia.
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Treatment Options for Male Infertility

Lifestyle and Health Improvements
Addressing lifestyle factors such as quitting smoking, reducing alcohol consumption, maintaining a healthy weight, and managing stress can improve sperm health.
Medical Treatments
+ Hormonal Therapy: Used to correct hormonal imbalances affecting sperm production.
+ Medications: Antibiotics to treat infections or medications to improve sperm production and function.
Assisted Reproductive Technologies (ART):
ART can help couples achieve pregnancy using methods such as:
+ Intrauterine Insemination (IUI): Sperm is processed and placed directly into the woman’s uterus to increase the chances of fertilization.
+ In Vitro Fertilization (IVF): Sperm is used to fertilize eggs in a lab, and the resulting embryos are transferred to the uterus.
+ Intracytoplasmic Sperm Injection (ICSI): A single sperm is injected directly into an egg to facilitate fertilization, commonly used in cases of severe male infertility.

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